Folliculitis means an inflamed hairfollicle due to any cause. The result is a tender red spot, often with a surface pustule.
Folliculitis may be superficial or deep. It can affect anywhere there are hairs, including chest, back, buttocks, arms, and legs. Acne and its variants are also types of folliculitis.
Spa pool folliculitis is due to infection with Pseudomonas aeruginosa, which thrives in warm water. Gram-negative folliculitis is a pustular facial eruption also due to infection with Pseudomonas aeruginosa or other similar organisms. When it appears, it usually follows tetracycline treatment of acne but is quite rare.
Yeasts
The most common yeast to cause a folliculitis is Pityrosporum ovale, also known as Malassezia. Malassezia folliculitis (pityrosporum folliculitis) is an itchy acne-like condition usually affecting the upper trunk of a young adult. Treatment includes avoiding moisturisers, stopping any antibiotics and using topical antifungal or oral antifungal medication for several weeks.
Ringworm of the scalp (tinea capitis) usually results in scaling and hair loss, but sometimes results in folliculitis. In New Zealand, cat ringworm (Microsporum canis) is the commonest organism causing scalp fungal infection. Other fungi such as Trichophyton tonsurans are increasingly reported. Treatment is with an oral antifungal agent for several months.
Viral infections
Folliculitis may be caused by the herpes simplex virus. This tends to be tender and resolves without treatment in around ten days. Severe recurrent attacks may be treated with aciclovir and other antiviral agents.
Herpes zoster (the cause of shingles) may present as folliculitis with painful pustules and crusted spots within a dermatome (an area of skin supplied by a single nerve). It is treated with high-dose aciclovir.
Molluscum contagiosum, common in young children, can present with follicularumbilicatedpapules, usually clustered in and around a body fold. Molluscum may provoke dermatitis.
Parasitic infection
Folliculitis on the face or scalp of older or immunosuppressed adults may be due to colonisation by hair follicle mites (demodex). This is known as demodicosis.
The human infestation, scabies, often provokes folliculitis, as well as non-follicular papules, vesicles and pustules.
Folliculitis due to irritation from regrowing hairs
Folliculitis may arise as hairs regrow after shaving, waxing, electrolysis, or plucking. Swabs taken from the pustules are sterile — there is no growth of bacteria or other organisms. In the beard area irritant folliculitis is known as pseudofolliculitis barbae (or folliculitis barbae if associated with an infection).
Irritant folliculitis is also common on the lower legs of women (shaving rash). It is frequently very itchy. Treatment is to stop hair removal, and not begin again for about three months after the folliculitis has settled. To prevent reoccurring irritant folliculitis, use a gentle hair removal method, such as a lady's electric razor. Avoid soap and apply plenty of shaving gel, if using a blade shaver.
Folliculitis due to contact reactions
Occlusion
Paraffin-based ointments, moisturisers, and adhesive plasters may all result in a sterile folliculitis. If a moisturiser is needed, choose an oil-free product, as it is less likely to cause occlusion.
Chemicals
Coal tar, cutting oils and other chemicals may cause an irritant folliculitis. Avoid contact with the causative product.
Topical steroids
Overuse of topical steroids may produce a folliculitis. Perioral dermatitis is a facial folliculitis provoked by moisturisers and topical steroids. Perioraldermatitis is treated with tetracycline antibiotics for six weeks or so.
Folliculitis may be due to drugs, particularly corticosteroids (steroid acne), androgens (male hormones), adrenocorticotrophic hormone (ACTH), lithium, isoniazid (INH), phenytoin and B-complex vitamins. Treatment with protein kinase inhibitors (epidermal growth factor receptor inhibitors) and targeted therapy for metastaticmelanoma (vemurafenib, dabrafenib) nearly always results in folliculitis.
Folliculitis due to inflammatory skin diseases
Certain uncommon inflammatory skin diseases may cause permanent hair loss and scarring because of deep-seated sterile folliculitis. These include:
Folliculitis affecting the buttocks is quite common in males and females.
Acute buttock folliculitis is usually bacterial in origin (like boils), resulting in red painful papules and pustules. It clears with antibiotics.
Chronic buttock folliculitis does not often cause significant symptoms but it can be very persistent. Although antiseptics, topical acne treatments, peeling agents such as alpha-hydroxy acids, long courses of oral antibiotics and isotretinoin can help buttock folliculitis, they are not always effective. Hair removal might be worth trying if the affected area is hairy. As regrowth of hair can make it worse, permanent hair reduction by laser or intense pulsed light (IPL) is best.
References
Durdu M, Ilkit M. First step in the differential diagnosis of folliculitis: cytology. Crit Rev Microbiol 2013; 39: 9–25. DOI: 10.3109/1040841X.2012.682051. PubMed