Author: DermNet Editor in Chief: Adjunct A/Professor Amanda Oakley, Dermatologist, Hamilton, New Zealand. Copy edited by Maria McGivern/Gus Mitchell. July 2018.
Marginalkeratoderma is a form of papularpalmoplantar keratoderma in which there are small firm warty or pearly papules on the sides of the hands and, in some cases, feet.
Probable acrokeratoelastoidosis
Keratoelastoidosis marginalis
Keratoelastoidosis marginalis
How is marginal keratoderma classified?
There are inherited and acquired forms of marginal keratoderma.
Inherited marginal keratoderma
The inherited form of marginal keratoderma is acrokeratoelastoidosis, which was first described by Costa in 1953; hence, it is sometimes called Costa acrokeratoelastoidosis. It affects both hands and feet.
The acquired form of marginal keratoderma is often called keratoelastoidosis marginalis and is more common than acrokeratoelastoidosis.
Keratoelastoidosis marginalis is characterised by keratotic papules on the sides of the index fingers and thumbs in patients who have had a lot of exposure to the sun.
Zanini Maurício. Focal acral hyperkeratosis: case report and discussion on marginal keratodermas. An Bras Dermatol 2006; 81(Suppl 3): S293–6. DOI: 10.1590/S0365-05962006000900009. Journal
Bhobe M, Tambe S, Jerajani H, Parulkar P. Keratoelastoidosis marginalis of the hands: A report in two farmers. Indian Dermatol Online J 2016; 7: 195–7. DOI: 10.4103/2229-5178.182364. PubMed Central
